Peter Z Schall

Peter uses advanced methods for analysis of RNA sequencing data to study mammalian reproductive tissues, oocytes, and embryos.

peter_schall.jpgResearch

Peter uses advanced methods for analysis of RNA sequencing data to study mammalian reproductive tissues, oocytes, and embryos. These studies include cross-species meta-analyses integrating expression data from multiple mammalian species with analysis of functional effects. The expectation is that the identification of genes that are regulated in common across species and the pathways and functions that they are associated with reveal new insights into the most salient mechanisms driving mammalian oogenesis and early embryogenesis.

Recent Publications

  • Eroglu B, Szurek EA, Schall PZ, Latham KE, Eroglu A. Probing lasting cryoinjuries to oocyte-embryo transcriptome. PLoS One. 2020;15(4):e0231108. doi: 10.1371/journal.pone.0231108. eCollection 2020. PubMed PMID: 32251418; PubMed Central PMCID: PMC7135251.
  • Schall PZ, Ruebel ML, Latham KE. A New Role for SMCHD1 in Life's Master Switch and Beyond. Trends Genet. 2019 Dec;35(12):948-955. doi: 10.1016/j.tig.2019.10.001. Epub 2019 Oct 25. Review. PubMed PMID: 31668908; PubMed Central PMCID: PMC6884149.
  • Ruebel ML, Vincent KA, Schall PZ, Wang K, Latham KE. SMCHD1 terminates the first embryonic genome activation event in mouse two-cell embryos and contributes to a transcriptionally repressive state. Am J Physiol Cell Physiol. 2019 Oct 1;317(4):C655-C664. doi: 10.1152/ajpcell.00116.2019. Epub 2019 Jul 31. PubMed PMID: 31365290; PubMed Central PMCID: PMC6850993.
  • Schall PZ, Ruebel ML, Midic U, VandeVoort CA, Latham KE. Temporal patterns of gene regulation and upstream regulators contributing to major developmental transitions during Rhesus macaque preimplantation development. Mol Hum Reprod. 2019 Mar 1;25(3):111-123. doi: 10.1093/molehr/gaz001. PubMed PMID: 30698740; PubMed Central PMCID: PMC6417155.

Outreach Project

Peter has volunteered at two science related functions: the MSU Science Olympiad State Tournament, and MSU Grandparents University. At the Olympiad, Peter proctored a middle/high school science competition. At Grandparent's University Peter helped out on activities relating to DNA, conveying his perspective on the importance of DNA science to multiple generations. Peter has also represented Michigan State University at an AAAS workshop in Washington D.C., focusing on scientific communication and proper technique for advocating for scientific research.

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