Center for PFAS Research

Dr. Sudin Bhattacharya is an Associate Professor in the Departments of Biomedical Engineering and Pharmacology & Toxicology, as well as the Institute for Quantitative Health Science and Engineering, at Michigan State University. He leads a lab conducting research at the interface of computation and biology, using quantitative tools to study the gene regulatory networks that underlie cell fate choice and its perturbation by environmental pollutants. His current work focuses on single-cell and spatial transcriptomics analysis in the context of cell fate choice and tissue architecture. Originally from Kolkata, India, Dr. Bhattacharya earned his undergraduate degree at Jadavpur University, his master’s degree at the University of Kentucky, and his Ph.D. at the University of Michigan, all in mechanical engineering. He did his postdoctoral training in computational biology at The Hamner Institutes for Health Sciences in North Carolina, USA. His work has been funded by the US Environmental Protection Agency and the National Institutes of Health.

Research Interests:

I am broadly interested in several areas of computational toxicology. A major focus of my work is the application of computational methods to study the signaling and transcriptional regulatory networks that underlie the determination of cell fate, and the perturbation of these networks by environmental pollutants like dioxin. Specifically, I am interested in integrating diverse genomic data sets to map and model transcriptional regulatory networks and their environmental perturbation in the immune system and the liver. I am also interested in the extraction of predictive features from genomic data sets to model the toxic potential of chemical agents and pharmaceuticals, and spatial multi-scale modeling of tissue-level phenomena like toxicant-induced liver injury. I rely primarily on mathematical and statistical modeling as a research tool, and work in close collaboration with experimental scientists. 

Educational Background:

Jadavpur University, India, B.M.E., 1997, Mechanical Engineering
University of Kentucky, M.S.M.E., 1999, Mechanical Engineering
University of Michigan, Ann Arbor, Ph.D., 2006, Mechanical Engineering

Selected Professional Activities:

Member, Society of Toxicology, 2007-present

Publications:

Google Scholar Citation Page: https://scholar.google.com/citations?user=woY4znwAAAAJ