Publications

Berryhill, G. E., Gloviczki, J. M., Trott, J. F., Aimo, L., Kraft, J., Cardiff, R. D., Paul, C. T., Petrie, W. K., Lock, A. L., & Hovey, R. C. 2012. Diet-induced metabolic change induces estrogen-independent allometric mammary growth. Proc. Natl. Acad. Sci. USA. 109(40), 16294–16299.

Rice, B. H., J. Kraft, F. Destaillats, D. E. Bauman, and A. L. Lock. 2012. Ruminant-produced trans-fatty acids raise plasma HDL particle concentrations in intact and ovariectomized female Hartley guinea pigs. J. Nutr. 142:1679–1683.

Berryhill, G. E., J. M. Gloviczki, J. F. Trott, L. Aimo, J. Kraft, R. D. Cardiff, C. T. Paul, W. K. Petrie, A. L. Lock, and R. C. Hovey. 2012. Diet-induced metabolic change induces estrogen-independent allometric mammary growth. Proc. Natl. Acad. Sci. USA. 109:16294–16299.

Weerasinghe, W. M. P. B., R. G. Wilkinson, A. L. Lock, M. J. De Veth, D. E. Bauman, and L. A. Sinclair. 2012. Effect of a supplement containing trans-10, cis-12 conjugated linoleic acid on the performance of dairy ewes fed 2 levels of metabolizable protein and at a restricted energy intake. J. Dairy Sci. 95: 109–116.

Kraft, J., J. I. Spiltoir, A. M. Salter and A. L. Lock. 2011. Differential effects of the trans-18:1 isomer profile of partially hydrogenated vegetable oils on cholesterol and lipoprotein metabolism in male F1B hamsters. J. Nutr. 141: 1819–1826.

Caldari-Torres, C., A. L. Lock, C. R. Staples, and L. Badinga. 2011. Performance, metabolic and endocrine responses of periparturient Holstein cows fed 3 sources of fat. J. Dairy Sci. 94: 1500–1510.

Rice, B. H., J. Kraft, F. Destaillats, D. E. Bauman, and A. L. Lock. 2010. Ruminant-produced trans-fatty acids raise plasma total and small HDL particle concentrations in male Hartley guinea pigs. J. Nutr. 140: 2173-2179.

Garnsworthy, P. C., S. Feng, A. L. Lock, and M. Royal. 2010. Heritability of milk fatty acid composition and Stearoyl-CoA desaturase indices in dairy cows. J. Dairy Sci. 93: 1743-1748.

Chen, S. X., M. Rovai, A. L. Lock, D. E. Bauman, T. A. Gipson, F. Z. Ran, and S. S. Zeng. 2009. Effects of milk fat depression induced by a dietary supplement containing trans-10, cis-12 conjugated linoleic acid on properties of semi-hard goat cheese. J. Dairy Sci. 92: 2534-2538.

Tyburczy, C., Major, C., A. L. Lock, F. Destaillats, P. Lawrence, J. T. Brenna, A. M. Salter, and D. E. Bauman. 2009. Individual trans octadecenoic acids and partially hydrogenated vegetable oil differentially affect hepatic lipid and lipoprotein metabolism in Golden Syrian hamsters. J. Nutr. 139: 257-263.

Tyburczy, C., A. L. Lock, D. A. Dwyer, F. Destaillats, Z. Mouloungui, L. Candy, and D. E. Bauman. 2008. Uptake and utilization of trans octadecenoic acids in lactating dairy cows. J. Dairy Sci. 91: 3850-3861.

Garnsworthy, P. C., A. Lock, G. E. Mann, K. D. Sinclair and R. Webb. 2008. Nutrition, metabolism and fertility in dairy cows: 2. Dietary fat content and ovarian function. J. Dairy Sci. 91: 3824-3833.

Garnsworthy, P. C., A. Lock, G. E. Mann, K. D. Sinclair and R. Webb. 2008. Nutrition, metabolism and fertility in dairy cows: 1. Dietary energy source and ovarian function. J. Dairy Sci. 91: 3814-3823.

Lock, A. L., M. Rovai, T. A. Gipson, M. J. de Veth, and D. E. Bauman. 2008. A conjugated linoleic acid (CLA) supplement containing trans-10, cis-12 CLA reduces milk fat synthesis in lactating goats. J. Dairy Sci. 91: 3291-3299.

Major, C. A., K. Ryan, A. J. Bennett, A. L. Lock, D. E. Bauman, and A. M. Salter. 2008. Inhibition of stearoyl Coenzyme A desaturase activity induces hypercholesterolaemia in cholesterol-fed hamsters. J. Lipid Res. 49: 1456–1465.

Castañeda-Gutiérrez, E., W. R. Butler. M. J. de Veth, A. L. Lock, D. A. Dwyer, K. D. Murphy, and D. E. Bauman. 2007. Effect of supplementation with Ca-salts of fish oil on omega-3 fatty acids in milk fat. J. Dairy Sci. 90: 4149-4156.

Sinclair, L. A., A. L. Lock, R. M. Early, and D. E. Bauman. 2007. Effects of a supplement containing trans-10, cis-12 conjugated linoleic acid on milk fat synthesis and cheese properties in dairy ewes fed two levels of energy. J. Dairy Sci. 90: 3326–3335.

Perfield II, J. W., A. L. Lock, A. Sæbø, J. M. Griinari, D. A. Dwyer, and D. E. Bauman. 2007. Trans-9, cis-11 conjugated linoleic acid (CLA) reduces milk fat synthesis in lactating dairy cows. J. Dairy Sci. 90: 2211-2218.

Lock, A. L., C. Tyburczy, D. A. Dwyer, K. J. Harvatine, F. Destaillats, Z. Mouloungui, L. Candy, and D. E. Bauman. 2007. Trans-10 octadecenoic acid does not reduce milk fat synthesis in dairy cows. J. Nutr. 137: 71-76.

Perfield II, J. W., P. Delmonte, A. L. Lock, M. P. Yurawecz, and D. E. Bauman. 2006. Trans-10, trans-12 conjugated linoleic acid (CLA) reduces the D9-desaturase index without affecting milk fat yield in lactating dairy cows. J. Dairy Sci. 89:2559-2566.

Garnsworthy, P. C., L. L. Masson, A. L. Lock, and T. T. Mottram. 2006. Variation of milk citrate with stage of lactation and de novo fatty acid synthesis in dairy cows. J. Dairy Sci. 89: 1604-1612.

Lock, A. L., B. M. Teles, J. W. Perfield II, D. E. Bauman, and L. A. Sinclair. 2006. A conjugated linoleic acid (CLA) supplement containing trans-10, cis-12 CLA reduces milk fat synthesis in lactating sheep. J. Dairy Sci. 89: 1525-1532.

Lock, A. L., C. A. M. Horne, D. E. Bauman, and A. M. Salter. 2005. Butter naturally enriched in conjugated linoleic acid and vaccenic acid alters tissue fatty acids and improves the plasma lipoprotein profile in cholesterol-fed hamsters. J. Nutr. 135: 1934-1939.

Lock, A. L., D. E. Bauman and P. C. Garnsworthy. 2005. Effect of production variables on the cis-9, trans-11 conjugated linoleic acid content of cows’ milk. J. Dairy Sci. 88: 2714-2717.

Lynch, J. M., A. L. Lock, D. A. Dwyer, R. Norbaksh, D. M. Barbano, and D. E. Bauman. 2005. Flavor and stability of pasteurized milk with elevated levels of conjugated linoleic acid and vaccenic acid. J. Dairy Sci. 88: 489-498.

Feng, S., A. L. Lock, and P. C. Garnsworthy. 2004. A rapid lipid separation method for determining fatty acid composition of milk. J. Dairy Sci. 87: 3785-3788.

Lock, A. L., B. A. Corl, D. E. Bauman, D. M. Barbano, and C. Ip. 2004. The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by D9-desaturase in rats. J. Nutr. 134: 2698-2704.

Perfield II, J. W., A. L. Lock, A. M. Pfeiffer, and D. E. Bauman. 2004. Effects of amide-protected and lipid-encapsulated conjugated linoleic acid (CLA) supplements on milk fat synthesis. J. Dairy Sci. 87: 3010-3016.

Lock, A. L. and P. C. Garnsworthy. 2003. Seasonal variation in milk conjugated linoleic acid and D9-desaturase activity in dairy cows. Livest. Prod. Sci. 79: 47-59.

Lock, A. L. and P. C. Garnsworthy. 2002. Independent effects of dietary linoleic and linolenic fatty acids on the conjugated linoleic acid content of cows' milk. Anim. Sci. 74: 163-176.

Invited Reviews

Bauman, D. E., K. J. Harvatine, and A. L. Lock. 2011. Nutrigenomics, rumen-derived bioactive fatty acids, and the regulation of milk fat synthesis. Annu. Rev. Nutr. 31: 299-319. (Available online at www.nutr.annualreviews.org).

Bauman, D. E., I. Mather, R. Wall, and A. L. Lock. 2006. Centennial Issue-Major Advances in Dairy Science in the Last Twenty-Five Years: Major Advances Associated with the Biosynthesis of Milk.  J. Dairy Sci. 89: 1235-1243.

Palmquist, D. L., A. L. Lock, K. J. Shingfield and D. E. Bauman. 2005. Biosynthesis of conjugated linoleic acid in ruminants and humans. In: S. L. Taylor (Ed.) Advances in Food and Nutrition Research, Vol. 50. pp. 179-217. Elsevier Inc., San Diego, CA, USA.

Conference Proceedings

Lock, A. L., and M. E. Van Amburgh. 2012. Feeding for milk components. Western Canadian Dairy Seminar Advances in Dairy Technology. Volume 24: 265-277.

Lock, A. L., and D. E. Bauman. 2011. Separating milk fats from fiction. Proc. Cornell Nutrition Conference. pp. 126-135.

Lock, A. L.. 2010. Update on dietary and management effects on milk fat. Proc. Tri-State Dairy Nutr. Conf. pp. 15-26.

Lock, A. L.. 2009. Milk fat challenges: from basic concepts to practical application. Proc. Mid Atlantic Nutr. Conf.

Lock, A. L., D. E. Bauman, and T. C. Jenkins. 2008. Understanding the biology of milk fat depression: from basic concepts to practical application. Proc. Intermountain Nutr. Conf. pp. 27-44.

Lock, A. L. and D. E. Bauman. 2007. Dietary component and rumen environment interactions on milk fat. Proc. 4-State Nutr. Conf. pp. 68-74.

Lock, A. L., W R. Butler, G. E. Mann and C. R. Staples. 2007. Can dietary fatty acid supplementation aid reproduction? Challenges and opportunities. Fertility in Dairy Cows: Bridging the Gaps, BSAS-EAAP Satellite Meeting. pp. 24.

Lock, A. L., T. R. Overton, K. J. Harvatine, J. G. Giesy, and D. E. Bauman. 2006. Milk fat depression: impact of dietary components and their interaction during rumen fermentation. Proc. Cornell Nutr. Conf. pp. 75-85.

Lock, A. L., K. J. Harvatine, J. K. Drackley, and D. E. Bauman. 2006. Concepts in fat and fatty acid digestion in ruminants. Proc. Intermountain Nutr. Conf. pp. 85-100. Available at:

Lock, A. L., K. J. Harvatine, I. R. Ipharraguerre, M. E. Van Amburgh, J. K. Drackley, and D. E. Bauman. 2005. The dynamics of fat digestion in lactating dairy cows: what does the literature tell us? Proc. Cornell Nutr. Conf. pp. 83-94.

Bauman, D. E., A. L. Lock, L. H. Baumgard, and R. C. Collier. 2004. Nutrient partitioning and milk yield: constraints and opportunities in the 21st century.  Proc. Cornell Nutr. Conf. pp. 107-121.

Lock, A. L., J. W. Perfield II, and D. E. Bauman. 2004. Trans fatty acids in ruminant-derived foods: fact and fiction. Proc. Cornell Nutr. Conf. pp. 123-134.

Bauman, D. E., J. W. Perfield II, M. J. de Veth, and A. L. Lock. 2003. New perspectives on lipid digestion and metabolism in ruminants. Proc. Cornell Nutr. Conf. pp. 175-189.

Michigan State University
  • Spartans Will.
  • © Michigan State University

MSU is an affirmative-action, equal-opportunity employer, committed to achieving excellence through a diverse workforce and inclusive culture that encourages all people to reach their full potential.

Michigan State University Extension programs and materials are open to all without regard to race, color, national origin, gender, gender identity, religion, age, height, weight, disability, political beliefs, sexual orientation, marital status, family status or veteran status. Issued in furtherance of MSU Extension work, acts of May 8 and June 30, 1914, in cooperation with the U.S. Department of Agriculture. Quentin Tyler, Director, MSU Extension, East Lansing, MI 48824. This information is for educational purposes only. Reference to commercial products or trade names does not imply endorsement by MSU Extension or bias against those not mentioned.

The 4-H Name and Emblem have special protections from Congress, protected by code 18 USC 707.

We comply with the Federal Trade Commission 1998 Children’s Online Privacy Protection Act (COPPA).